C-type lectin receptor信号通路
WebFeb 18, 2024 · C-type lectin-like receptors (CLRs) represent a family of transmembrane pattern recognition receptors, expressed primarily by myeloid cells. They recognize not … WebFeb 14, 2024 · The C-type lectin receptor Dectin-1 was originally described as the β-glucan receptor expressed in myeloid cells, with crucial functions in antifungal responses. However, over time, different ligands both of microbial-derived and endogenous origin have been shown to be recognized by Dectin-1. The outcomes of this recognition are diverse, …
C-type lectin receptor信号通路
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WebThe IL-17 receptor family includes IL-17 R/IL-17RA, IL-17B R/IL-17RB, IL-17RC, IL-17RD/SEF, and IL-17RE. All of these receptor subunits are type I transmembrane … WebC-type lectin receptor that binds carbohydrates mannose and fucose but also weakly interacts with N-acetylglucosamine (GlcNAc) in a Ca 2+-dependent manner (PubMed:27015765). Involved in regulating immune reactivity (PubMed:18258799, PubMed:10438934). Once triggered by antigen, it is internalized by clathrin-dependent …
WebC型凝集素是一类含有钙离子(Ca2+)依赖糖识别域(Carbonhydraterecognition domain,CRD)的蛋白超家族,是固有免疫系统中的重要模式识别受体(Pattern-recognition receptor,PRR)。 … WebApr 5, 2016 · Englisch: C-type lectin receptor. Definition. C-Typ-Lektin-Rezeptoren, kurz CTLs, sind eine Klasse von Pattern-Recognition-Rezeptoren, die spezifisch Kohlenhydrate erkennen. Über die Bindung von PAMPs erkennen sie Pathogene und lösen eine Immunantwort aus. Biochemie.
WebOct 1, 2015 · The C-type lectins are the largest and most diverse of the lectin families found in animals. C-type lectins contain an independently folding, modular carbohydrate-recognition domain (CRD) that in most cases binds sugars by ligation to Ca 2+, making the sugar-binding activity Ca 2+ -dependent [ 2]. Many receptors containing C-type CRDs …
WebOverview of RIG-I-like Receptors. The RIG-I-like receptors (RLRs) are a family of cytosolic pattern recognition receptors that are essential for detecting viral RNA and initiating the innate immune response. The RLR …
WebMar 30, 2024 · C-type lectin receptor signaling pathway 04650 Natural killer cell mediated cytotoxicity 04612 N Antigen processing and presentation 04660 N T cell receptor signaling pathway ... G protein-coupled receptors. 07220 Cholinergic and anticholinergic drugs 07215 alpha-Adrenergic receptor agonists/antagonists 07214 beta-Adrenergic receptor … impacts of childhood traumaWebCollectins (collagen-containing C-type lectins) are a part of the innate immune system.They form a family of collagenous Ca 2+-dependent defense lectins, which are found in animals.Collectins are soluble pattern recognition receptors (PRRs). Their function is to bind to oligosaccharide structure or lipids that are on the surface of microorganisms. list three characteristics of covalent bondsWebJun 15, 2011 · The C-type lectins are one of the pattern recognition receptors (PRRs) with lectin-like carbohydrate recognition domains (CRDs) in their extracellular … impacts of climate change gcse geographyWebC-type lectin receptors (CLRs) have an important role in orchestrating the induction of signalling pathways that regulate adaptive immune responses. CLRs can control adaptive immunity at various ... impacts of childhood obesityWebJul 22, 2024 · Accordingly, we herein examined the effects of combined stimulation of NLR (NOD1/2) and Syk-coupled lectin receptors (Dectin-1/Mincle) in comparison to individual PRR stimulation in vitro as well as in vivo. This is the first report showing that combined stimulation of NOD1/2 and C-type lectin receptors potentiates the activity of key ... impacts of child marriageWebCLEC7A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with a partial immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition … impacts of chronic neglect on childrenWeb1. 受体(receptor)和配体(ligand) 2. 蛋白激酶(kinase) 3. 转录因子(transcription factors) 1、受体(receptor)和配体(ligand) 受体(Receptor): 指一类能传导细胞外信号,并在细胞内产生特定效应的分子。包括膜受体和胞内受体。 impacts of cholera