Cigarette smoke theophylline

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August undefined, 2024

WebTheophylline disposition was examined in seven passive smokers, defined as nonsmokers with long-term exposure to cigarette smoke, and seven age-matched nonsmokers with minimal smoke exposure. Subjects were given an intravenous infusion of aminophylline (6 mg/kg) and blood samples were drawn before and during the 48-hour postinfusion period. Web20 hours ago · At the end of March, Altria Group MO –0.19% (ticker: MO) said it wants revenue from smoke-free products in the U.S. to double by 2028 following its purchase …

How Smoking Affects Medications - Pharmacy Times

WebTheophylline comes as an extended-release (long-acting) tablet, extended-release capsule, and a solution (liquid) to take by mouth. It usually is taken every 6, 8, 12, or 24 hours. ... WebApr 22, 2024 · Theophylline is an oral medication used to treat asthma and other lung diseases. ... Smoking: Smoking cigarettes or marijuana can affect the amount of … hideout\u0027s wh

Theophylline Side Effects, Dosage, Uses & More - Healthline

WebFeb 26, 2013 · Theophylline is metabolized in the liver by the cytochrome P450 microsomal enzyme system, and a large number of factors may influence hepatic metabolism. … WebElimination half-life and apparent volume of distribution of theophylline were determined in ten healthy volunteers who used smokeless tobacco (snuff or chewing tobacco) regularly but did not smoke cigarettes. Serum concentrations of the acute phase reactant α1-acid glycoprotein (AAC) were also measured. The elimination half-life of theophylline was … WebThe effects of cigarette smoking and sex on theophylline clearance, elimination rate constant, and apparent volume of distribution were examined in 28 healthy, young adults … hideout\u0027s wi

The Influence of Cigarette Smoking and Sex on Theophylline …

Drug interactions with smoking American Journal of Health …

http://robholland.com/Nursing/Drug_Guide/data/monographframes/T025.html WebDec 15, 2012 · Theophylline clearance can be decreased by a high carbohydrate-low protein diet, as well as the ingestion of other methylxanthines such as caffeine. In contrast, a low carbohydrate-high protein diet, especially charcoal broiled meat, may enhance theophylline clearance. Theophylline clearance is markedly increased by tobacco or … hideout\\u0027s wiWebMay 16, 2016 · With smoking cessation, the risk of harming the patient still exists, as abruptly stopping cigarette smoking can make a patient feel uncomfortable and may even cause additional harm. ... Theophylline (Theo-24) Since these medications are substrates of the enzyme being induced (CYP1A2), smoking will lower the drug concentration of … how fans only works

"WebOthers were cardiovascular disturbances (1.2 percent), effects on the central nervous system (0.9 percent), and miscellaneous adverse reactions (0.9 percent). A higher … " - Cigarette smoke theophylline

Cigarette smoke theophylline

Theophylline American Journal of Respiratory and Critical Care …

WebThe pharmacokinetics of theophylline were examined in a group of nonsmokers and in heavy smokers (1 to 2 packs/day) before and 3 to 4 mo after cessation of cigarette smoking. The half-life of theophylline in smokers averaged 4.3 (SD = 1.4) hr, significantly shorter than the mean value in nonsmokers (7.0, SD = 1.7 hr). WebSmoking cigarettes (not the nicotine) increases the metabolism of some medicines by stimulating the hepatic enzyme CYP1A2. ... Action to take when stopping smoking; …

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WebAnalyses of urinary metabolites revealed that clearance to l-methyluric acid (Cl1MU) and clearance to 3-methylxanthine (Cl3MX) were increased in smokers 1.99-fold and 2.10-fold over nonsmoking controls (P less than 0.005). Clearance to 1.3-dimethyluric acid (ClDMU) was also enhanced in smokers 1.68-fold compared to controls (P less than 0.01). Webheavy smokers (20-40 cigarettes per day) may need much higher doses of than non-smokers; full normalisation of hepatic function appears to take many months or even years after stopping aminophylline or theophylline ; High (narrow therapeutic index drug) When stopping smoking: a reduction in theophylline dose of up to 25-33% might be needed ...

WebThe pharmacokinetics of theophylline were examined in a group of nonsmokers and in heavy smokers (1 to 2 packs/day) before and 3 to 4 mo after cessation of cigarette … WebDocument: BACKGROUND: Chronic bronchitis is a disease of the bronchi that is manifested by cough and sputum expectoration occurring on most days for at least 3 months of the year and for at least 2 consecutive years when other respiratory or cardiac causes for the chronic productive cough are excluded. The disease is caused by an interaction between …

WebThe pharmacokinetics of theophylline were examined in a group of nonsmokers and in heavy smokers (1 to 2 packs/day) before and 3 to 4 mo after cessation of cigarette … WebDec 28, 2024 · IL-8 (A) and TNF-α (B) levels in C2C12 cells pretreated with theophylline or pyrrolidine dithiocarbamate (PDTC) for 2 h before incubation with vehicle control or cigarette smoke extract (CSE). NF-κBp65 mRNA ( C ) and protein ( D ) levels in C2C12 cells pretreated with theophylline or PDTC for 2 h before incubation with vehicle control …

WebSep 15, 2007 · Tobacco smoke consists of two phases: the vapor (or gaseous) and particulate phases. Of the estimated 4800 compounds in tobacco smoke, the majority are found in the particulate phase. 1 Nicotine, a natural substance found in tobacco leaves, is the major component of the particulate phase. 2 Nicotine comprises 1.5% of the total …

WebCigarette smoking can result in an increase of as much as threefold in CYP1A2 activity. 44 Theophylline is metabolized in part by CYP1A2, 45 which explains why smokers require higher doses of ... how fantasy hockey worksWebMar 1, 2024 · Theophylline is structurally classified as a methylxanthine. Theophylline, USP occurs as a white crystalline powder. Anhydrous Theophylline has the chemical name 1,3-dimethyl-3,7-dihydro-1-H … how fantasy football waivers workWebWhen cigarette smokers with chronic lung disease stop smoking, they may do so with the aid of chewing nicotine gum. Smoking is known to accelerate the metabolism of theophylline, but the effects of nicotine gum on theophylline metabolism have not been determined. We studied the effects of nicotine a … hideout\\u0027s wjWebTheophylline, which has a narrow therapeutic window, is predominantly metabolised by CYP1A2 and increased clearance of 60–100% has been demonstrated in smokers,. … how fantasy cricket worksWebTheophylline (Elixophyllin, Theo-24) is a bronchodilator prescribed for the treatment of asthma and other airway conditions. Side effects, drug interactions, dosage, and … how far a body part can move in any directionWebTheophylline, also known as 1,3-dimethylxanthine, is a phosphodiesterase inhibiting drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine, and is … how far above a bathtub should the spout beWebIn a prospective study in 73 patients with obstructive pulmonary disease, aged 63.5±13.5 years (SD), it was found that theophylline dose, cigarette smoking and age were all significant determinants of the steady-state trough plasma theophylline level during oral administration of the drug. As the predictive efficiency of the three factors combined … how fantasy points are scored