Cyp17a1蛋白

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August undefined, 2024

Webcyp17a1蛋白属于细胞色素p450氧化酶超家族的一员，定位于内质网，既有甾体的17α-羟化酶也有17,20-裂合酶活性，在类固醇生成途径中将孕烯醇酮或孕酮的d环上17号c原子上α … WebFeb 22, 2024 · CYP17A1 ；, CPT7, CYP17, P450C17, S17AH, cytochrome P450 family 17 subfamily A member 1 外部ID OMIM ： 609300 MGI ： 88586 HomoloGene ： 73875 GeneCards ： CYP17A1

CYP19A1 Rabbit Polyclonal Antibody (CYP19A1 兔多抗)(AF6231)

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Structures of cytochrome P450 17A1 with prostate cancer …

WebDefects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5) [MIM:202410]. AH5 is a form of congenital adrenal hyperplasia, a common recessive disease due to … WebApr 9, 2024 · 本研究主要探讨新疆阿魏中的化学物质、抗癌的作用机制及可能作用的靶点，通过网络药理学研究帮助筛选新疆阿魏的药效物质基础，对进一步研究其抗肿瘤作用单体成分及作用靶点提供理论基础。. 1方法. 1.1新疆阿魏有效成分及靶点的筛选. 利用草药-中医证候 ... WebThe CYP17A1 gene provides instructions for making a member of the cytochrome P450 enzyme family. Like other cytochrome P450 enzymes, CYP17A1 is involved in the … cities skylines starting layout 2021

CYP17A1 - an overview ScienceDirect Topics

WebEach serum sample from cyp17a1 +/+ XX, cyp17a1 +/+ XY, cyp17a1 –/– XX, and cyp17a1 –/– XY fish was measured in 2 dilutions and each dilution was assayed in duplicate. All necessary reagents including buffer, standard, serum samples, tracer, and antiserum, were sequentially loaded into the corresponding wells according to the ... Web1 day ago · 春季常吃哪些食物护肝？. 以下是春季养肝护肝的一些食物：. 1.苦味食物：苦瓜、黄芩、枸杞子等具有清热解毒的作用，适量食用可以促进胆汁分泌，帮助肝脏排毒。. … diary of dreams - the valleyWebCYP17A1慢病毒激活颗粒(h)包含以下SAM激活元素：一种是去活化的Cas9 (dCas9)核酸酶(D10A and N863A)，它融合了转录活化域VP64；一种是MS2-p65-HSF1融合蛋白；一种 … cities skylines stadt layout

"Web进一步实验证实CPSF6是通过APA调节作用于下游靶点基因人宫颈癌癌基因2(HCCR2)，使其具有缩短3'UTR的转录本高表达，翻译更多的蛋白，进而调节肝癌的增殖和转移过程。另外，实验中发现let-7a、let-7c、miR-26a三种miRNA结合在CPSF6基因3'UTR上直接抑制基因的 … " - Cyp17a1蛋白

Cyp17a1蛋白

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WebJan 22, 2012 · Cytochrome P450 17A1 (also known as CYP17A1 and cytochrome P450c17) catalyses the biosynthesis of androgens in humans. As prostate cancer cells proliferate in response to androgen steroids, CYP17A1 inhibition is a new strategy to prevent androgen synthesis and treat lethal metastatic castration-resistant prostate cancer, but drug … Web反馈墙 ( 0) 通用注释. 亚单元: N/A. 功能: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.

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细胞色素 P450 17A1（英語：Cytochrome P450 17A1）也被称为甾体17α-单加氧酶（steroid 17α-monooxygenase），17α-羟基化酶（17α-hydroxylase），17,20-碳链裂解酶（17,20-lyase 或 17,20-desmolase）是一种羟基化酶，由位于人类10号染色体的 CYP17A1 基因编码。这一基因在许多组织与细胞中都有表达，特别是肾上腺皮质的网状带（英语：zona reticularis）和 … Web目的探讨细胞色素P450c17a酶 (CYP17A1)在人神经胶质瘤细胞系T98G,U87和U251中的表达情况.方法采用Western blot和实时荧光定量PCR于蛋白质水平和mRNA水平检测细胞色素P450c17a酶 (CYP17A1)在三种人胶质瘤细胞系中的表达.结果 Western blot检测出CYP17A1蛋白在胶质瘤细胞系T98G,U251和 ...

Web说明书. CYP17A1 抗体 D-12 是小鼠单克隆 IgG 2a κ， CYP17A1抗体, 在 12篇文献中引用，规格为 200 µg/ml. 免疫原氨基酸序列461-508位于human物种的CYP17A1的C … WebCYP17A1 ( シトクロム P450 17A1, steroid 17-alpha-monooxygenase 17α-hydroxylase/17,20 lyase/17,20 desmolase) はヒトにおいて CYP17A1 遺伝子がコードす …

Web肾上腺皮质腺瘤CYP17A1及3BHSD2蛋白的免疫组化研究. 目的:应用免疫组织化学染色方法观察17α羟化酶 (CYP17A1),3β羟基类固醇脱氢酶2 (3BHSD2)在人正常肾上腺及其肿瘤组织中的分布特点,探讨CYP17A1,3BHSD2免疫组化检测对病理诊断肾上腺醛固酮分泌腺瘤 (APA),皮质醇分泌腺瘤 ... Webcyp17a1蛋白屬於細胞色素p450氧化酶超家族的一員，定位於內質網，既有甾體的17α-羥化酶也有17,20-解離酶活性，在類固醇生成途徑中將孕烯醇酮或孕酮的d環上17號c原子上α …

WebThe CYP17A1 gene provides instructions for making a member of the cytochrome P450 enzyme family. Like other cytochrome P450 enzymes, CYP17A1 is involved in the formation (synthesis) of steroid hormones. This group of hormones includes sex hormones such as testosterone and estrogen, which are needed for normal sexual development and …

Web作为胆汁酸合成限速酶, cyp7a1的表达受饮食因素的调控. 日本研究者发现在7周龄的sd雄性大鼠中, 给予乳酸发酵的豆奶饲食5 wk后, rt-pcr显示肝组织中cyp7a1的mrna表达较对照 … diary of eating straights 30WebCYP17A1蛋白屬於細胞色素P450 氧化酶超家族的一員，定位於內質網，既有甾體的17α-羥化酶也有17,20-解離酶活性，在類固醇生成途徑中將孕烯醇酮或孕酮的D環上17號C … diary of dreams wikipediaWebCYP17A1 is on Chromosome 15q23 and codes a 57 kDa enzyme that catalyzes two oxidase reactions resulting in a hydroxylation and a cleavage (lyase activity). The zone … diary of dreams wikiWebCYP17A1. Cytochrome P450 17A1 ( steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10. [5] It is ubiquitously expressed in many tissues and cell types, including the zona reticularis and zona ... cities skylines starting guideWebFeb 22, 2024 · 结构 [] 基因 []. CYP17A1 基因位于10号染色体的10q24.3带上包含有8个外显子，其cDNA全长为1527bp。. 蛋白 []. CYP17A1蛋白大小为57.4kDa ，包含有508个氨基酸残基，属于CYP450超家族，带有一个血红素相关活性位点以催化相关生物反应。. CYP17A1可被两种甾类抑制剂阿比特龙（英语： abiraterone ）和galeterone特异 ... diary of early winter shower 1998Web发明领域. 本发明涉及制备苯并咪唑化合物，其用作p300和/或CBP活性调节剂和因此能够用作药物物质。发明背景 cities skylines statue of shoppingWeb肾上腺皮质腺瘤CYP17A1及3BHSD2蛋白的免疫组化研究. 目的:应用免疫组织化学染色方法观察17α羟化酶 (CYP17A1),3β羟基类固醇脱氢酶2 (3BHSD2)在人正常肾上腺及其肿瘤 … diary of dreams melancholic