Phospho-acss2
WebAnti-ACSS2 Antibody (A-9) is a mouse monoclonal IgG 1 κ ACSS2 antibody, cited in 5 publications, provided at 200 µg/ml raised against amino acids 1-160 mapping at the N-terminus of ACSS2 of human origin Anti-ACSS2 Antibody (A-9) is recommended for detection of ACSS2 of mouse, rat and human origin by WB, IP, IF and ELISA WebMar 8, 2024 · Influenza virus is responsible for respiratory diseases that can be severe or even lethal, especially in young children and the elderly 1.The virus causes annual …
Phospho-acss2
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Web3.1.3 Phospholipase A2 Inhibition. Phospholipase A2 (PLA2), which cleaves phospholipids producing lysophospholipids and free fatty acids, was originally identified as an …
WebDeacetylates ACSS2 leading to its activation, and HMGCS1. Involved in liver and muscle metabolism. ... All lanes : Anti-SIRT1 (phospho T530) antibody [EPNCIR153] (ab156585) at 1/1000 dilution Lane 1 : 293T cell lysates Lane 2 : 293T cell lysates treated with Calyculin A Lysates/proteins at 10 µg per lane. Secondary WebThis gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl - …
WebNutritional stresses, which restrict acetyl-CoA production from glucose or acetate uptake, result in AMPK-mediated phosphorylation and nuclear translocation of ACSS2. ACSS2 binds to TFEB, translocates to lysosomal and autophagosomal gene promoter regions, and incorporates acetate from histone acetylation turnover to locally produce acetyl-CoA for … WebNational Center for Biotechnology Information
WebJul 7, 2024 · Acetyl-CoA synthetase 2 (ACSS2) is a crucial member of the acetyl-CoA synthetase (ACSS) family and is transcribed from the ACSS2 gene. The ACSS2 gene, first isolated from yeast cells, encodes two isoforms produced by alternative transcription start site selection, with lengths of 1606 bp and 2106 bp [ 8 ].
Web(orb1096966) ACSS2 (Phospho-Ser659) Antibody Sign in or register to save this reagent to your favourites Supplier Biorbyt Host Rabbit Type Primary Clonality Polyclonal Conjugate … fish lake management district hancock wiWebMay 31, 2024 · ACSS2 seems to bind to the promoters of immediate early genes before memory consolidation, implying that acetate, rather than ACSS2, is the limiting factor for histone acetylation at these genes. can chlordiazepoxide be taken as neededWebIn the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from … fish lake mackinaw campground mapWebMay 25, 2024 · In the nucleus, ACSS2 binds to transcription factor EB and translocates to lysosomal and autophagy gene promoter regions, where ACSS2 incorporates acetate generated from histone acetylation turnover to locally produce acetyl-CoA for histone H3 acetylation in these regions and promote lysosomal biogenesis, autophagy, cell survival, … fishlake meadowsWebTreatment with biguanides, but not isotretinoin, significantly upregulated ACSS2 gene expression in primary sebocytes and showed synergism with lipogenic activators to induce DNL genes. ... Phospho-mTOR signals were determined by absorbance at 450nm using a SpectraMax iD3 plate reader (Molecular Devices, San Jose, CA). Statistical Analysis. can chlorine affect plateletsWebAug 26, 2016 · ACSS2 is highly upregulated in multiple cancer types and may be a useful biomarker for anti-ACSS2 therapies. [ 11 C]acetate has demonstrated excellent potential as an alternative positron emission ... can chlorhexidine gluconate cause bad breathWebSep 18, 2024 · Acetyl-CoA synthetase 2 (ACSS2) is a conserved nucleocytosolic enzyme that converts acetate to acetyl-CoA. Adult mice lacking ACSS2 appear phenotypically normal but exhibit reduced tumor burdens in mouse models of liver cancer. The normal physiological functions of this alternate pathway of acetyl-CoA synthesis remain unclear, … fish lake marcellus michigan