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Adaptive evolution driving the young duplications in six Rosaceae ...
WebMay 24, 2016 · A naturally occurring tandem duplication of the Alcohol dehydrogenase (Adh) gene exhibits 2.6-fold greater expression than the single-copy gene in transgenic Drosophila This tandem duplication also exhibits greater activity than two copies of the gene in trans, demonstrating that it is the tandem arrangement and not copy number that is the ... WebApr 14, 2024 · Therefore, segmental duplication, rather than tandem duplication, seems to be the main evolutionary mechanism for the expansion and functional diversification of the Snf2 gene family. The evolution of new gene functions usually results from the combined effects of duplication and selection. tooth abscess vs sinus infection
The tandem duplicator phenotype as a distinct genomic ... - PNAS
WebAug 11, 2024 · Tandem duplication (TD) is an important type of structural variation (SV) in the human genome and has biological significance for human cancer evolution and … WebAug 2, 2012 · The MLL-partial tandem duplication (PTD) associates with high-risk cytogenetically normal acute myeloid leukemia (AML).Concurrent presence of FLT3-internal tandem duplication (ITD) is observed in 25% of patients with MLL-PTD AML.However, mice expressing either Mll-PTD or Flt3-ITD do not develop AML, suggesting that 2 mutations … Webdata:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAKAAAAB4CAYAAAB1ovlvAAAAAXNSR0IArs4c6QAAAw5JREFUeF7t181pWwEUhNFnF+MK1IjXrsJtWVu7HbsNa6VAICGb/EwYPCCOtrrci8774KG76 ... tooth abscess under a crown